ASSESSMENT OF CHEMICAL PROFILE AND ANTIOXIDANT POTENTIAL IN AQUEOUS EXTRACTS OF DIFFERENT ANATOMICAL PARTS OF ARRABIDAEA CHICA (BIGNONIACEAE) FROM TABATINGA, AM

Resumo

Arrabidaea chica, commonly known as "pariri," "cipó-pau," or "crajiru," boasts numerous medicinal properties, including the treatment of various ailments such as uterine and ovarian inflammation, syphilis, leukemia, conjunctivitis, diarrhea, and psoriasis, among others. Despite its extensive use in traditional medicine, its pharmacological potential remains underestimated, with fewer than 50 studies conducted in the last decade, and only four focused on the Amazon region. This study aimed to analyze the chemical profile and determine the antioxidant potential of aqueous extracts from different anatomical parts of A. chica collected in Tabatinga. Material collected underwent exsiccate preparation and extract extraction. Exsicata were deposited in the Didactic Herbarium UEA/CESTB, while extracts were analyzed for antioxidant activity and mass spectrometry. Stem, root, and leaf extracts showed antioxidant potential mainly in the leaves (88%). Mass spectrometry revealed six flavonoids: Vicenin II, Scutellarein-O-glucuronide, 6-Hydroxyluteolin-O-glucuronide, 6-Methoxyluteolin-O-glucuronide, Scutellarein-(6 "-O-cafeoyl)-glucopyranoside, and Carajurin. These findings underscore A. chica high pharmacological potential, especially its antioxidant activity, and the identification of bioactive compounds, primarily flavonoids, holds promise for pharmaceutical and cosmetic applications, positioning A. chica as a valuable resource for future research and biotechnological advancements.